Publications

1. Soll,D.R., Voss,E., Varnum-Finney,B. and Wessels,D. 1988. The "Dynamic Morphology System": a method for quantitating changes in shape, pseudopod formation and motion in normal mutant amoebae of Dictyostelium discoideum. J. Cellular Biochem. 37:177-192.

2. Soll, D.R. 1988. "DMS", a computer-assisted system for quantitating motility, the dynamics of cytoplasmic flow and pseudopod formation: its application to Dictyostelium chemotaxis. In: "Optical Approaches to the Dynamics of Cellular Motility" (ed. J. Condeelis). Supplement to Cell Motil. Cytoskel. 10, 91-106.

3. Soll,D.R., Voss,E. and Wessels,D. 1988. Development and application of the "Dynamic Morphology System" for the analysis of moving amoebae. SPIE Proceedings, Vol. 832 (ed. H.C.Johnson), pp. 21-30.

4. Soll,D.R. 1988. DMS, a Computer-Assisted System for Quantitating Motility, the Dynamics of Cytoplasmic Flow and Pseudopod Formation: its Application to Dictyostelium Chemotaxis. In: Optical Approaches to the Dynamics of Cellular Motility: ( ed. J. Condeelis). Supplement to Cell Motil. Cytoskel. 10: 91-106.

5. Soll,D.R., et al, 1988. Development and Application of the Dynamic Morphology System for the Analysis of Moving Amebae. SPIE Proceedings, Vol. 832 (ed. H.C.Johnson). pp. 21-30.

6. Vale,R.D., Soll,D.R. and Gibbons, I.R. 1989. One-dimensional diffusion of microtubules bound to flagellar dynein. Cell 59: 915-925.

7. Wessels,D., Schroeder,N., Voss,E., Hall,A., Condeelis,J. and Soll,D.R. 1989. cAMP mediated inhibition of intracellular particle movement and actin reorganization in Dictyostelium. J. Cell Biol. 109: 2841-2851.

8. Wessels,D. and Soll,D.R. 1990. Myosin II heavy chain null mutant of Dictyostelium exhibits defective intracellular vesicle movement. J. Cell Biol. 111:1137-1148.

9. Brady-Kalnay,S., Soll,D.R. and Brackenbury,R. 1991. Invasion of rous sarcoma virus-transformed retinal cells: role of cell motility. Internat. J.Cancer 47: 560-568.

10. Fukui,Y., Voss,E., Riddelle,K.S. and Soll,D.R. 1991. Cell behavior and actomyosin organization in Dictyostelium during substrate exploration. Cell Struct. Funct. 16: 289-301.

11. Brady-Kalnay,S.M., Boghaert,E.R., Zimmer,S., Soll,D.R. and Brackenbury,R. 1991. Invasion by WC5 rat cerebellar cells is independent of RSV-induced changes in growth and adhesion. Internat. J. Cancer 49: 239-245.

12. Wessels,D., Murray,J., Jung,G., Hammer,J. and Soll,D.R. 1991. Myosin IB null mutant of Dictyostelium exhibits abnormalities in motility. Cell Motil. Cytoskel. 20:301-315.

13. Hegmann,T.E., Schulte,D.L., Lin,J.L.-C. and Lin,J.J.-C. 1991. Inhibition of intracellular granule movement by microinjection of monoclonal antibodies against caldesmon. Cell Motil. Cytoskel. 20: 109-120 (1991).

14. Kim,Y.-T. and Wu,C.-F.. 1991. Distinctions in growth cone morphology and motility between monopolar and multipolar neurons in Drosophila CNS cultures. J.Neurobiol. 22: 263-275.

15. Cox,D., Condeelis,J., Wessels,D., Soll,D.R., Kern,H. and Knecht,D.A. 1992. Targeted disruption of the ABP-120 gene leads to cells with altered motility. J. Cell Biol. 116: 943-955

16. Alexander, S., Sydow, L., Wessels, D. and Soll, D.R. 1992. Dictyostelium mutants lacking the discoidium lictins are defective in pseudopod extension and morphology, but still maintain cell polarity. Differenttion 51:149-161.

17. Wessels,D., Murray,J. and Soll,D.R. 1992. The complex behavior cycle of chemotaxing Dictyostelium amoebae is regulated primarily by the temporal dynamics of the natural wave. Cell Motil. Cytoskel. 23: 145-156.

18. Segall,J., 1992. Behavioral responses of streamer F mutants of Dictyostelium discoideum: effects of cyclic GMP on cell motility. J. Cell Sci. 101: 589-597.

19. Titus,M., Wessels,D., Spudich,J. and Soll,D.R. 1992. The unconventional myosin encoded by the myo A gene plays a role in Dictyostelium motility. Molec. Biol. Cell 4: 233-246.

20. Sylwester,A., Wessels,D., Anderson,S.A., Warren,R.Q., Shutt,D., Kennedy,R. and Soll,D.R. 1993. HIV-Induced syncytia of a T cell line form single giantpseudopods and are motile. J. Cell Science 106: 941-953.

21. Wessels,D., Vawter-Hugart,H., Murray,J. and Soll,D.R. 1994. Three dimensional dynamics of pseudopod formation and turning during the motility cycle of Dictyostelium. Cell Motil. Cytoskel. 27: 1-12.

22. Soll,D.R., and Kennedy,R. 1994. The role of T cell motility and cytoskeletal reorganization in HIV-induced syncytium formation: a perspectus. AIDS Res. and Hum. Ret. 10:325-327

23. Chandrasekhar, A., Wessels, D., and Soll, D.R. 1995. A mutation that depresses cGMP phosphodiesterase activity in Dictyostelium affects cell motility through an altered chemotactic signal.. Develop. Biol. 169: 109-122.

24. Sylwester,A., Shutt,D., Wessels,D., Stapleton,J.T., Stites,J., Kennedy,R., and Soll,D.R. 1995. T cells and HIV-induced T cell syncytia exhibit themotility cycle. J. Leuk. Biol. 57: 643-650.

25. Royal,D., Royal,M.-A., Italiano,J., Roberts,T. and Soll,D.R.1995. In Ascaris Sperm Psudopods, MSP Fibers Move Proximally at a Cosntant Rate Regardless of Forward Rate of Cellular Translocation. Cell Motil. Cytoskel. 31:241-253.

26. Shutt,D,. Stapleton,J., Kennedy,R. and Soll,D.R. 1995. HIV-induced syncytia of peripheral blood T cells mimic the organization of individual cells and translocate through extension of giant pseudopodia. Cell. Immun. 166:261-274.

27. Shutt,D., Wessels,D., Chandrasekhar,A., Luna,B., Hitt,A. and Soll, D.R. 1995. Ponticulin plays a role in the spatial stabilization of pseudopods. J. Cell Biol. 131:1495-1506.

28. Shelden,E, and Knecht,D. 1995. Mutants lacking myosin II resist forces generated during 108: 1105-1115.

29. Cox,D., Wessels,D., Soll,D.R., Hartwig,J., and Condeelis,J. 1996. Re-expression of ABP-120 rescues cytoskeletal, motility and phagocytosis defects of ABP-120- Dictyostelium mutants. Molec. Biol. Cell. 7: 803-823.

30. Wessels,D., Titus,M., and Soll,D.R. 1996. A Dictyostelium myosin I plays a crucial role in regulating the frequency of pseudopods formed on the substratum. Cell Motil. Cytoskel. 33: 64-79.

31. Warren,K., Shutt,D.C., McDermott,J.P., Lin,J.L., Soll,D.R.and Lin,J.J. 1996. Overexpresion of microfilament-stabilizing human caldesmon fragment, CaD39, affects cell attachment, spreading and cytokinesis. Cell Motil. Cytoskel. 34: 215-229.

32. Mizuno,T., Kagami,O., Sakai,T. and Kawasaki,K. 1996. Locomotion of neutrophil fragments occurs by graded radial extension. Cell Motil. Cytoskel. 35: 289-297.

33. Aizawa,H., Sutoh,K. and Yahara,I. 1996. Overexpression of cofilin stimulates bundling of actin filaments, membrane ruffling, and cell movement in Dictyostelium. J. Cell Biol. 132: 335-344.

34. Shelden,E., and Knecht,D. 1996. Dictyostelium cell shape generation requires myosin II. Cell Motility and the Cytoskeleton, 35: 59-67.

35. Cox,D., et al, 1996. Targeted disruption of the ABP-120 gene leads to cells with altered motility. J. Cell Biol. 116:943-955.

36. Warren,K.S., Shutt,D.C., McDermott,J.P., Lin,J.L-C., Soll,D.R. and Lin,J.J-C. 1996. Overexpression of microfilament-stabilizing human caldesmon fragment, CaD39, affects cell attachment, spreading and cytokinesis. Cell Motil Cytoskel. 34: 215-229.

37. Kim,Y.-T., and Wu,C.-F. 1996. Reduced growth cone motility in cultured neurons from Drosophila memory mutants with a defective cAMP cascade. J. Neurosci. 16: 5593-5602.

38. Sylwester,A., Shutt,D., Murphy,S., and Soll.,D.R. 1997. HIV-induced T cell syncytia are self-perpetuating and the primary cause of T cell death in culture. J. Immun. 158, 3996-4007.

39. Stites,J., Wessels,D., Uhl,A., Egelhoff,T.E. Shutt,D. and Soll,D.R. 1997. Interpreting the role of myosin heavy chain (MHC) phosphorylation through a computer-assisted behavioral analysis of a Dictyostelium mutant which can not phosphorylate the MHC tail region. Cell Motil. Cytoskel. 39: 31-51.

40. Sylwester, A., Daniels, K. and Soll, D.R. 1997. The invasive and destructive behavior of HIV-induced T cell syncytia on collagen and endothelium. J. Leuk. Biol. 63: 233-244.

41. Royal,D., Royal M.A., LHernault,S. and Soll,D.R. 1997. Quantitative analysis of Caenochabditis elegans sperm motility and how it is affected by mutants spe11 and unc54. Cell Motil. Cytoskel. 37: 98-110.

42. Soll,D.R. 1997. Researchers in cell motility and the cytoskeleton can play major roles in understanding AIDS. Cell Motil. Cytoskel. 37: 91-97.

43. Esenlante, R., Wessels, D., Soll, D.R. and Loomis, W.F. 1997. Chemotaxis to cAMP and slug migration in Dictyostelium both depend on MigA, a BTB protein. Molec. Biol. Cell. 8: 1763-1775.

44. Aizawa,H, Sameshima,M. and Yahara,I. 1997. A green fluorescent protein-actin fusion protein dominantly inhibits cytokinesis, cell spreading, and locomotion in Dictyostelium. Cell. Struct. Funct. 22: 335-345.

45. Leberer,E., Wu,C., Leeuw,T., Fourest-Lieuvin,A., Segall,J.E.and Thomas,D.Y. 1997. Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase. EMBO Journal 16: 83-97.

46. Esenlante,R., Wessels,D., Soll,D.R. and Loomis,W.F. 1997. Chemotaxis to cAMP and slug migration in Dictyostelium both depend on MigA, a BTB protein. Molec. Biol. Cell 8: 1763-1775.

47. Wu,C.-F. 1997. Neuronal growth cone motility: contributions from neurogenetic analysis of cultured Drosophila neurons. In Motion Analysis of Living Cells, D. Soll, editor. John Wiley and Sons, New York, N.Y., pp. 235-261.

48. Wang,J.W., A.W. Sylwester, D. Reed, D.-A.J. Wu, D.R. Soll, and C.-F. Wu. 1997. Morphometric description of the wandering behavior in Drosophila larvae: aberrant locomotion in Na+ and K+ channel mutants revealed by computer-assisted motion analysis. J. Neurogenet. 11: 231-254.

49. Taft,P.J., Hoffmann,F.M. and C.-F.Wu. 1997. The Drosophila ableson tyrosine kinase: effects on neuronal adhesion and growth cone motility in cell culture. Abstr. Ann. Drosophila Res. Conf. 38: 203.

50. Cammer,M., Wyckoff,J. and Segall,J.E. 1997. Computer-assisted analysis of single-cell behavior. Methods in Molecular Biology. 75, 459-481.

51. Shutt,D.C., Jenkins,L.M., Daniels,K., Kennedy,R., Stapleton,J., and Soll,D.R. 1998. T cell syncytia induced by HIV release T cell chemoattractants: demonstration with a newly developed single cell chemotaxis. J. Cell Sci. 111: 99-109.

52. Wessels,D. and Soll,D.R. 1998. Computer-assisted analysis of cytoskeleton mutants of Dictyostelium. In Motion Analysis of Living Cells, ed. D.R. Soll and D. Wessels. John Wiley, Inc. pp. 101-140.

53. Soll,D.R. and Voss,E. 1998. Two and three dimensional computer systems for analyzing how cells crawl. In Motion Analysis of Living Cells, ed. D.R. Soll, D. Wessels. John Wiley, Inc. pp.25-52.

54. Wessels,D., Voss,E., Von Bergen,N., Burns,R., Stites,J., and Soll,D.R. 1998. A computer-assisted system for reconstructing and interpreting in three dimensions the relationships of the cell surface, the nucleus and pseudopods in living cells. Cell Motil. Cytoskel. 41: 225-246.

55. Wu,X., Bowers,B., Rao,K., Wei,Q. and Hammer,J.A. 1998. Visualization of Melanosome Dynamics within Wild-Type and Dilute Melanocytes Suggests a Paradigm for Myosin V Function in Vivo. J Cell Biol. 143: 1899-1918.

56. de Bono,M., Bargmann,C.I. 1998. Natural Variation in a Neuropeptide Y Receptor Homolog Modifies Social Behavior and Food Response in C. elegans. Cell 94: 679-689.

57. Farina,K. L., Wyckoff,J.B., Rivera,J., Lee,H., Segall,J.E., Condeelis,J.S. and Jones,J.G. 1998. Cell Motility of Tumor Cells Visualized in Living Intact Primary Tumors Using Green Flourescent Protein. Cancer Res. 58: 2538-2532.

58. Wyckoff,J. B., Insel,L., Khazaie,K., Lichtner,R.B., Condeelis,J.S. and Segall,J.E. 1998. Suppression of ruffling by the EGF receptor in chemotactic cells. Experimental Cell Research 242: 100-109.

59. Bailly,M., Yan,L., Whitesides,G.M., Condeelis,J.S. and Segall,J.E. 1998. Regulation of Protrusion Shape and Adhesion to the Substratum during Chemotactic Responses of Mammalian Carcinoma Cells. Exp. Cell Res. 241: 285-299.

60. Wang,Y., Liu,J. and Segall,J.E. 1998. MAP kinase function in amoeboid chemotaxis. J. Cell Sci. 111: 373-383.

61. Wu,C.-F., Renger,J.J. and J.E. Engel. 1998. Functional and developmental plasticity of Drosophila neurons. Adv. Insect Physiol. 17:285-340.

62. Wong,K., Wessels,D., Krob,S.L., Lin,J.L-C., Soll,D.R., and Lin, J.J-C. Forced expression of a dominant-negative chimeric tropomyosin causes abnormal motile behavior during cell division. in preparation.

63. Wessels,D., Reynolds,J., Johnson,O., Voss,E., Burns,R., Daniels,K., Garrard,E., OHalloran,T. and Soll,D.R. 1999. Clathrin plays a role in the regulation of cell shape, cell polarity, pseudopod formation and motility in Dictyostelium. Submitted.

64. Shutt,D., Daniels,K., Stapleton,J.T., Carolan,E., Kealey,G.P., Cederna,P.S., Goeken,J.A., Kennedy,R.C. and Soll,D.R. 1999. Motile syncytia in the lymph nodes of HIV-infected individuals. Submitted.

65. Shutt,D.C. and Soll,D.R. 1999. HIV-induced T-cell syncytia release a two component T-helper cell chemoattractant composed of Nef and Tat. Submitted.

66. Wong,K., Wessels,D., Krob,S., Matveia,A.R., Lin,J.L., Soll,D.R. and Lin,J.J. 2000. Forced expression of dominant-negative chimaric tropomyosin causes abnormal motile behavior during cell division. Cell Motil. Cytoskel., 45, 121-132.

67. Wessels,D., Reynolds,J., Johnson,O., Voss,E., Burns,R., Daniels,K., Garrard,E., O'Hallaran,T., and Soll,D.R. 2000. Clathrin plays a novel role in the regulation of cell polarity, pseudopod formation, uropod stability and motility in Dictyostelium. J. Cell Sci., 113, 26-36.

68. Soll,D.R., Voss,E., Johnson,O. and Wessels,D.J. 2000. Three-dimensional reconstruction and motion analysis of living crawling cells. Scanning 22, 249-257.

69. Wessels,D., Zhang,H., Reynolds,J., Daniels,K., Heid,P., Liu,S., Kuspa,A.,Shaulsky,G., Loomis,W.F. and Soll,D.R. 2000. The internal phoshodiesterase RegA is essential for the suppression of lateral pseudopods during Dictyostelium chemotaxis. Molec. Bilo. Cell 11, 2803-2820.

70. Shutt,D.C., Daniels,K., Carolan,E.J., Hill,A. and Soll,D.R. 2000. Changes in the motility, morphology and F-actin architecture of human dendritic cells in an in vitro model of dendritic cell development. Cell Motil. Cytoskel. 46, 200-221.

71. Soll,D.R., Wessels,D., Voss,E. and Johnson,O. 2001. Computer-assisted systems for the analysis of amoeboid cell motility. In Methods in Molecular Biology: Cytoskeleton Methods and Protocols (ed. R.H. Gavin). Humana Press, Inc. Totowa, N.J., pp 45-58.

72. van Es,S., Wessels,D., Soll,D.R. and Devreotes,P. 2001. Tortoise, a novel mitochondrial protein, is required for directional responses of Dictyostelium in chemotatic gradients. J. Cell Biol. 152, 621-632.

73. Tuxworth,R., Weber,I., Wessels,D., Addicks,G.C., Soll,D.R., Gerisch,G. and Titus,M. 2001. A role for myosin VII in dynamic cell adhesion. Current Biol. 11, 1-20.

74. Wang,J.W., Soll,D.R. and Wu,C.-F. 2002. Morphometric description of the wandering behavior in Drosophila larvae: phenotypic analysis of K+ channel mutants. J. Neurogenet. in press.

75. Zhang,H., Wessels,D., Fey,P., Chisholm,R. and Soll,D.R. 2002. Phosphorylation of the myosin regulatory light chain plays a role in cell motility and polarity in Dictyostelium chemotaxis. J. Cell Science. 115, 1733-1745.

76. Heid,P.,Voss,E. and Soll,D.R. 2002. 3D-DIASemb: a computer-assisted system for reconstructing and behaviorally analyzing in 4D every cell and nucleus, and monitoring cytoplasmic flow in a developing embryo. Develop. Biol. 245(2): 1-19.

77. Shutt,D.C., Stapleton,J., Daniels,K., Carolan,E., Kealey,G.P., Cederna,P.S., Gocken,J.A., Kennedy,R.C. and Soll,D.R. 2002. Motile syncytia reside in the lymph nodes of HIV-infected individuals. HIV and Hum. Ret., under revision.

78. Shutt,D., Daniels,K. and Soll,D.R. 2002. The human immunodeficiency virus (HIV) causes human dendritic cells to retract dendritic processes, polarize and crawl. J. Leuk. Biol., under revision.

79. Steiner,J., Wessels,D., Soll,D.R. and Saxe,C.L. 2002. SCAR, a WASP-related protein, is essential for lateral pseudopod formation and chemotaxis in Dictyostilium. J. Cell Biol., under revision.

80. Bosgraaf,L., Russcher,H., Smith,J.C., Wessels,D., Soll,D.R. and Van Haastert,P.J.M. 2002. A novel cGMP-signaling pathway mediating myosin phosphorylation and chemotaxis in Dictylostelium. EMBO, in press.

81. Chubb,J.R., Wilkins,A., Wessels,D.J., Soll,D.R. and Insoll,R. 2002. Cell movement and Ras in Dictyostelium: related mutants cause rapid migration by different mechanisms. Cell Motel. Cytoskel., in press.

82. Han,Y.-H., Chung,C.Y., Stephens,S., Titus,M.A., Wessels,D.J., Soll,D.R. and Firtel,R.A. 2002. Requirement of VASP for cell adhesion, filopodia formation and chemotaxis. submitted to J. Cell Biol.

83. Soll,D.R. 2002. A contextual framework for interpreting the roles of proteins in motility and chemotaxis in Dictyostelium discoideun. In preparation.

84. Zhang,H., Heid,P., Wessels,D., Daniels,K., Pham,T., Loomis,W.F. and Soll,D.R. 2002. cAMP-dependent protein kinase A (PKA) functions downstream of RegA in the suppression of lateral pseudopods during Dictyostelium chemotaxis. In preparation.

85. Barelle,C.J., Bohula,E.A., Kron,S.J., Wessels,D., Soll,D.R., Schafer,A., Grown,A.J.P. and Gow,N.A.R. 2002. Asynchronons cell cycle in true hyphai of Candida ablicans is related to asymmetric vacuolar inheritance. In preparation.